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Clinical Evidence Search

Gill 2025: ASPN Consensus Guidelines for 60-day PNS
Summary
  • First clinical guideline specifically assessing the clinical use of 60-day PNS
  • 60-day PNS received received strong to moderate recommendations for several pain conditions
  • Strong recommendations  made in chronic back pain, postoperative knee pain, and post-amputation pain
Vorenkamp 2025: Shoulder Pain Follow-up Survey after 60-Day PNS
Summary
  • A majority of responders to 60-day PNS reported sustained shoulder pain relief in a follow-up survey
  • Through up to 5 years, over 80% avoided advancing to additional interventions for shoulder pain
  • A majority of patients interested in deferring shoulder surgery successfully did so after 60-day PNS
Gutierrez 2025: 60-Day PNS of the Occipital Nerves for Headache
Summary
  • Primary endpoint from a prospective study (n=20) shows headache relief after 60-day PNS
  • 85% of participants at end of treatment had at least 50% reductions in pain and/or pain interference
  • Ongoing follow-up indicates that relief is sustained in a majority of participants
Gilmore 2025: 4-Year Follow Up After 60-day PNS in Low Back Pain
Summary
  • Long-term follow-up survey for prior study shows outcomes in back pain 4 years after 60-day PNS
  • Majority of respondents reported sustained relief of back pain an average of 4.7 years after PNS
  • 70% avoided progression to more costly, invasive, and/or destructive low back pain interventions