Clinical Evidence Search

Clinical Evidence Search

Gutierrez 2024: PNS for CRPS Case Reports
Summary
  • SPRINT PNS was used to treat complex regional pain syndrome (CRPS).
  • Three cases of CRPS in the lower extremity with significant and sustained relief of pain.
  • These three cases suggest that 60-day PNS can be a safe and efficacious treatment for CRPS.
Kelly 2023: PNS Retrospective Case Series in Chronic Knee Pain
Summary
  • Retrospective case series (n=14): PNS targeting femoral and saphenous nerves for chronic knee pain
  • 75% reported ≥50% pain reduction; 52% average pain relief at six months post-implantation
  • Demonstrated safety and efficacy with no adverse events
Mach 2023: Case series of lumbar PNS for cancer-related back pain
Summary
  • PNS for pain secondary to myeloma-related spinal lesions enabled pain relief for radiation therapy
  • Lumbar medial branch PNS is a promising option for back pain from primary or metastatic tumors
  • Four patients successfully used lumbar PNS for pain relief, allowing them to complete radiation
Tate 2023: Technical Case Report on PNS of Musculocutaneous Nerve
Summary
  • Completed ultrasound-guided placement of short-term PNS lead targeting musculocutaneous nerve (MCN)
  • Patient had total pain resolution & coverage in antecubital & radial forearm areas during 60-Day PNS
  • Ultrasound-guided placement of PNS is feasible for targeting the MCN in refractory elbow pain
Moman 2021: PNS for Refractory Occipital Neuralgia (Case Report)
Summary
  • Single patient case report of temporary PNS (GON) followed by permanent PNS for occipital neuralgia
  • Temporary PNS provided resolution of pain and discontinuation of opioids during treatment of ON
  • Pain returned after removal. A permanent lead was implanted and provided relief for 12 months
Fiala 2022: Case Series of Lumbar Level PNS for Low Back Pain
Summary
  • Six reports of PNS targeting the lumbar medial branches for low back pain.
  • Patients reported an average 65% pain reduction with PNS.
  • Medial branch PNS may provide pain relief and functional improvements to those with refractory CLBP.
Chitneni 2022: Case Reports of PNS in Rotator Cuff Pathology
Summary
  • Two reports of suprascapular & axillary nerve PNS for chronic shoulder pain after rotator cuff tear
  • Reported 80-90% pain relief and 50%-75% opioid reduction 3-months after completing 60-day PNS
  • 60-day PNS may provide sustained relief of rotator cuff pain recalcitrant to conservative treatments
Woodbury 2021: Cervical PNS for Occipital Neuralgia Case Report
Summary
  • Novel percutaneous PNS approach targeting C2-3 medial branches for occipital neuralgia
  • Case report of patient with 80% headache pain reduction after 8 weeks of PNS treatment
  • Longitudinal C2-3 approach is less technically challenging than the traditional C1 transverse method
Shaw 2021: PNS for Post-thoracotomy Intercostal Pain Case Reports
Summary
  • Two reports of durable relief (13-14 months) following 60-day PNS of intercostal nerves.
  • 60-Day PNS of intercostal nerves for chronic post-thoractomy intercostal neuralgia.
  • PNS may reduce opioid and nonopioid medication usage in intercostal neuralgia pain.
Mainkar 2020: Pilot Study in Termporary PNS in Oncologic Pain
Summary
  • Case series (n=12) demonstrates promising peripheral targets for the treatment of oncologic pain
  • Successful PNS targeting spinal nerves, brachial plexus, and peripheral nerves for oncological pain
  • Successful relief in 7 of 12 cases, with several reporting relief beyond lead removal
Haider 2023: Case Report of Cervical PNS in Arthritic Neck Pain
Summary
  • Patient experienced 2 years of severe chronic pain following a work-related neck injury.
  • Physical therapy and over-the-counter pain medications did not provide sufficient relief.
  • PNS targeting the nerves of the cervical spine produced 50% reduction in pain at 2 months.