Clinical Evidence Search | SPR

Clinical Evidence Search

Filtered By

Gill 2025: ASPN Consensus Guidelines for 60-day PNS

Summary

First clinical guideline specifically assessing the clinical use of 60-day PNS
60-day PNS received received strong to moderate recommendations for several pain conditions
Strong recommendations made in chronic back pain, postoperative knee pain, and post-amputation pain

Pritzlaff 2024: Review of Studies on PNS for Chronic Pain

Summary

Ten studies were identified that prospectively studied PNS for treatment of chronic pain.
The studies included patients with shoulder pain, neuropathic pain, or low back pain.
Reductions in pain and/or pain interference were consistently reported across all pain types.

Staats 2021: Surveys of Patient Preference for LBP Interventions

Summary

Study using two market research surveys of chronic pain patient preferences for LBP interventions.
LBP patients preferred temporary interventions to permanently implanted devices.
Temporary PNS was the most preferred treatment option over RFA and permanent implants.

Deer 2021: Proposed Mechanism of Action for Percutaneous PNS

Summary

Discusses potential mechanisms by which PNS may provide prolonged reductions in pain.
Remote selective targeting with PNS may produce robust comfortable sensations in the area of pain.
Prolonged pain relief may occur as a reversal of maladaptive cortical plasticity driven by PNS.

Gupta 2020: Cadaveric Feasibility of Intercostal PNS Implantation

Summary

Cadaveric study assessing ultrasound-guided intercostal PNS implantation
12 stimulators implanted between 5th and 10th ribs bilaterally between intercostal muscles
Average lead-to-nerve distance: 2.3 mm (SPR MicroLead) and 1.1 mm (StimRouter)