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Clinical Evidence Search

Sheth 2026: Real-world, cross-sectional survey in low back pain
Summary
  • Follow-up survey reporting real-world outcomes up to 5 years after 60-day PNS in low back pain
  • 79% of those surveyed reported avoiding RFA, permanent implants, and surgery through follow-up
  • Of those avoiding interventions, 79% reported improvement in at least one health domain at follow-up
Li 2026: Per Protocol Analysis of 60-Day PNS for CLBP (RESET RCT)
Summary
  • Post hoc analysis of RESET RCT suggests 60-day PNS treatment delivery is associated with outcomes
  • Other explored variables (e.g., response to MBB) were not significantly associated with outcomes
  • Exploratory cohorts with facetogenic and discovertebral pain features reported positive outcomes
Aman 2026: Predictors of Success in Shoulder Pain Chart Review
Summary
  • Retrospective chart review shows relief across a variety of shoulder pain types and histories
  • Bimodal PNS® treatment produced greater response rate compared to sensory or motor stimulation alone
  • Similar outcomes in EMR and manufacturer data highlight consistency across data sources
Sheth 2025 ASRA: 5-Year Real-World Outcomes of 60-Day PNS in LBP
Summary

ASRA, low back pain, follow-up survey, long-term durability, intervention avoidance, Denise Lester, Jaudat Mahmood, Sarah Trampota, Lawson Smith, Raheleh Rahimi, Brandon Swan, Meredith McGee, Joseph Boggs