Clinical Evidence Search | SPR

Clinical Evidence Search

Sheth 2023 NANS: Occipital PNS for head and neck pain RWD

Hagedorn 2023 ASRA: RWE for PNS among Medicare-Eligible Cohort

Reece 2023 ASPN: Multi-domain Improvements in Knee Pain with PNS

Tate 2023: Technical Case Report on PNS of Musculocutaneous Nerve

Summary

Completed ultrasound-guided placement of short-term PNS lead targeting musculocutaneous nerve (MCN)
Patient had total pain resolution & coverage in antecubital & radial forearm areas during 60-Day PNS
Ultrasound-guided placement of PNS is feasible for targeting the MCN in refractory elbow pain

Kelly 2023: PNS Retrospective Case Series in Chronic Knee Pain

Summary

Retrospective case series (n=14): PNS targeting femoral and saphenous nerves for chronic knee pain
75% reported ≥50% pain reduction; 52% average pain relief at six months post-implantation
Demonstrated safety and efficacy with no adverse events

Pingree 2022: Long-Term Follow-Up Survey Following 60-Day PNS

Summary

Cross-sectional follow-up survey of SPRINT PNS patients.
Most patients reported meaningful pain relief and/or improvement in quality of life at follow up.
About one third of survey respondents also reported reducing or stopping medication use.

Shah 2022 ASRA: 60-Day PNS in Shoulder Pain RWD

Naidu 2022: Real-World Analysis of Delayed Response to PNS

Summary

60-day PNS treatment can help identify delayed responders and non-responders to stimulation
38% of patients (n=747) were either delayed responders (31%) or delayed non-responders (7%)
60-day PNS may help inform treatment strategies to optimize outcomes and cost for patients

Chitneni 2022: Case Reports of PNS in Rotator Cuff Pathology

Summary

Two reports of suprascapular & axillary nerve PNS for chronic shoulder pain after rotator cuff tear
Reported 80-90% pain relief and 50%-75% opioid reduction 3-months after completing 60-day PNS
60-day PNS may provide sustained relief of rotator cuff pain recalcitrant to conservative treatments

Fiala 2022: Case Series of Lumbar Level PNS for Low Back Pain

Summary

Six reports of PNS targeting the lumbar medial branches for low back pain.
Patients reported an average 65% pain reduction with PNS.
Medial branch PNS may provide pain relief and functional improvements to those with refractory CLBP.

Moman 2021: PNS for Refractory Occipital Neuralgia (Case Report)

Summary

Single patient case report of temporary PNS (GON) followed by permanent PNS for occipital neuralgia
Temporary PNS provided resolution of pain and discontinuation of opioids during treatment of ON
Pain returned after removal. A permanent lead was implanted and provided relief for 12 months

Shaw 2021: PNS for Post-thoracotomy Intercostal Pain Case Reports

Summary

Two reports of durable relief (13-14 months) following 60-day PNS of intercostal nerves.
60-Day PNS of intercostal nerves for chronic post-thoractomy intercostal neuralgia.
PNS may reduce opioid and nonopioid medication usage in intercostal neuralgia pain.